The yeast metabolome addressed by electrospray ionization mass spectrometry: Initiation of a mass spectral library and its applications for metabolic footprinting by direct infusion mass spectrometry
Jesper Hojer Pedersen and Jorn Smedsgard
Presenters:
Niki Arinze and Liwei Jiang
Posts
Tommy Byrd
ReplyDeletePedersen and Smedsgard
1. Accurate mass spectroscopy techniques provide an efficient means to profile the metabolic profile of yeast mutants
2. Can you explain positive and negative mode and what the difference is between them? What exactly is "metabolic footprinting" and what are some of its other applications?
3. ESI digram
4. What SyBBURE or Viibre groups are working with metabolic profiles, if any?
Samat Kabani
ReplyDeletePedersen and Smedsgard
1. Yeast metabolites can be accurately identified using mass spectrometry, allowing for better classification methods on ionization of the metabolites.
2. How does one derive biological information based on "guilt-by-association?"
3. Pros and Cons of Positive and Negative Mode MS
Rachel Harvey
ReplyDeletePendersen and Smedsgard
1. By using ESI it was possible to analyze the metabolites of yeast.
2. What exactly is an in silico metabolome?
3. Yeast metabolites &metabolic differences in yeast
Elizabeth
ReplyDeletePendersen and Smedsgard
1. ESI mass spec can be used to analyze the metabolites of yeast with a high mass efficiency.
2. So is this better than plain mass spec because it can distinguish between 2 metabolites of the same mass but with different charge.
3. Othe uses of ESI MS